Jiang-Fan Chen

Jiang-Fan Chen

Wenzhou Medical University, Professor

Dr. Jiang-Fan Chen has a long-standing interest in adenosine receptor neurobiology with focus on in adenosine A2A receptor control of physiological (cognition and sleep) and pathological (ischemia and neurodegeneration) processes.   Dr. Chen’s work contributes to the development and eventual FDA approval of the A2A receptor antagonist (istradefylline) for treatment of Parkinson’s disease.   Dr. Chen’s recent work has focused on the eye-brain neuronal connections and functional interactions, leading to the discovery of 40Hz light flicker improve sleep and glymphatic activity via adenosine signaling.   Dr. Chen has published 280 papers on adenosine neurobiology in primary neuroscience journals, with H index = 83.